MDMA Literature Reviews

3,4-Methylenedioxymethamphetamine (MDMA)
A Review of the English-Language Scientific and Medical Literature

Reid Stuart, M.A.

July 13, 2001

2001 MDMA Literature Review (PDF, 4.2 MB)
Part 1 – Table of Contents, Introduction and Chapter Summaries (303K)
Part 2 – Previous Human Experience: Controlled Clinical Trials and Pharmacology (865K)
Part 3 – Demographics and Self-Reported Effects of Illicit Ecstasy Use (471K)
Part 4 – MDMA Neurotoxicity: Studies in Nonhuman Animals (1M)
Part 5 – Neurotoxicity Research in Humans (376K)
Part 6 – Medical Emergencies and Adverse Events in Ecstasy Users (289K)
Part 7 – References (532K)
Part 8 – Appendices (973K)

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Updates are intended to keep the literature review current by providing summaries of all papers that discuss MDMA or ecstasy, with a focus on human clinical trials and studies in ecstasy users. All updates include summaries of original research and reviews of studies conducted in humans, in vitro and in non-human animals published in English-language peer-reviewed journals.

Further information about these papers can be found in the MAPS MDMA Bibliography. You can check out new citations, reviews and summaries at

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