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With a few exceptions, only studies in which psychedelics are actually administered to human subjects
are included in the following list of projects.
Studies in which psychedelic drug users are compared to control groups are generally not included.
Animal studies are not included.
For comprehensive bibliographies of past psychedelic research, including all therapeutic studies as well as
other human and animal studies, see our bibliography section.
For more information about psychedelic psychotherapy, see
"Psychedelic Psychotherapy and Spirituality: The Ten Lessons of Psychedelics, Rediscovered"
by Neal Goldsmith, Ph.D. along with the
associated bibliography
and
viewgraph presentation.
This page is updated by Ilsa Jerome, Ph.D. If you have any questions, or more recent information
about any of these studies, please write .
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See also the MDMA Research Page for more links.
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MDMA-assisted Psychotherapy in the Treatment of Post Traumatic Stress
Disorder (PTSD)
Investigators: Michael Mithoefer, MD
Location: Charleston, South Carolina
Sponsor: MAPS
Contact:
The protocol was approved by FDA on
November 2, 2001. The protocol was modified in June 2002 when FDA approved the
move of the location of the treatment sessions to Dr. Mithoefer's office. In
July 2002, the Western IRB approved the protocol, only to revoke approval in
September 2002 as a result of internal pressure. In response to an appeal by
MAPS, which included 12 letters of support for the protocol from scientists
around the world, the Western IRB refused to review the underlying scientific
data, decided the study was too controversial, withdrew from the review and
returned all fees paid by MAPS. On September 23, 2003, a new IRB approved the protocol after a
three month review process. The DEA issued Dr. Mithoefer his Schedule I licence on February 24th, 2004, nearly a year and a half after he applied for it. Dr. Mithoefer is now in the process of recruiting and screening potential study volunteers.
[ See MAPS' MDMA page ]
MAPS needs to raise $425,000 for this study ($280,000 for the study and $145,000 on the protocol design and prolonged approval process) and has already raised about $310,000 ($113,000 from John Gilmore, $58,000 from the Joe Barnhart Foundation, $35,000 from the Overbrook Foundation, $50,000 from an anonymous family foundation, $12,800 from Anja Saunders,$10,000 from Shawn Hailey, $10,000 from Richard Wolfe, $10,000 from the Zimmer Family Foundation, $5,000 from Michael Ziegler, $5,000 from an anonymous donor, $1,780 from the Holland Fund, plus a few smaller donations). We are now seeking to raise the remaining $115,000. [ See the MDMA
Clinical Plan ]
Last updated April 12, 2004.
Serotonin and Dopamine system interactions in the reinforcing properties of psychostimulants
Investigators: Manny Tancer, MD and Charles Schuster, PhD
Wayne State University - Detroit, Michigan, USA
Contact:
Sponsor: NIDA
Psychobiological studies approved and in process. An MDMA dose-response study and a comparison of MDMA, d-amphetamine
and mCPP are completed. The first paper about this research was published in December, 2001, and
a second report was published in November 2003.
Last updated February 23, 2004.
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See also the
MDMA Research Page for more
links.
MDMA-assisted Psychotherapy in the Treatment of Post Traumatic Stress
Disorder (PTSD)
Location: Israel
Sponsor: MAPS
This study is presently inactive - efforts to resume this project will commence after MAPS has obtained FDA,
IRB and DEA approval of the PTSD study directed by Michael Mithoefer, M.D., in South Carolina (USA).
Read about the 1999
Israel MDMA Conference
MAPS-Supported MDMA/PTSD Research in Israel: An Update
Rick Doblin PhD.
MAPS Bulletin, Vol. 13, No. 1, Spring 2003
also available:
Attack of the Happy People - An Israeli
documentary about Ecstasy which includes a discussion of MAPS' Israeli MDMA/PTSD project
Last updated January 2, 2004
MDMA Psychotherapy in the Treatment of Post Traumatic Stress Disorder — Spain Study
Investigators: Pedro Sopelana Rodriguez, psychiatrist at the Psychiatric
Hospital of Madrid (Hospital Psiquiatrico de Madrid); Jose Carlos Bouso Saiz, Ph.D. candidate
U. de Autonoma de Madrid, Spain
Contact:
Sponsor: MAPS
A pilot dose-finding study with the purpose of gathering information to be used to help select the dose for a
subsequent study of therapeutic efficacy. The project is the first formal therapy study with MDMA ever conducted.
Six of the 29 subjects have now been treated. We have completed treating the patients in the 50 mgs dose group
(3 patients received 50 mgs and 1 received a placebo), and have treated two people in the 75 mg dose group (5
patients will receive 75 mgs and 2 will receive a placebo). Unfortunately, this study has been shut down for political
reasons due to pressure on the hospital from the Madrid AntiDrug Authority, though we are working to overcome these
obstacles. The Ministry of Health has not withdrawn permission, so there is a chance that the study can be resumed,
though definitely not until sometime after we obtain permission to start the US MDMA/PTSD study.
See the current update, the protocol and the informed consent form.
Last updated February 24, 2004
MDMA Dose Response Study in Cancer Patients with Anxiety
Investigators: John Halpern MD,
Harvard Medical School and McLean Hospital, Belmont MA
Contact:
Funding: MAPS
Study of MDMA-assisted psychotherapy in subjects with anxiety as a result of end-stage cancer, with outcome measures to
evaluate anxiety, pain and quality of life. On February 23, 2004, MAPS donated $11,000 to McLean Hospital, Harvard Medical School, for
Dr. Halpern's work on the protocol design and approval process ($15,000 was also donated to McLean for this study on June 2003). MAPS
had initially worked with Dr. Charles Grob in a much earlier effort to conduct MDMA research in cancer patients prior to Dr. Grob's switching to psilocybin
(see entry below). For more information about Dr. Grob's effort. see the details and reference page,
the 1995 version of the protocol, and
view the video. .Dr. Halpern's study is currently under development and will hopefully commence near
the end of 2004.
Last updated February 24, 2004
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Behavioral Effects of MDMA Related to Driving Ability
Investigators: C.T.J. Lamers PhD, J.G. Ramaekers PhD, W.J. Riedel
University of Maastricht, the Netherlands
Contact:
Sponsor: Ministry of Transport, the Netherlands
This research examines MDMA effects on driving related task performance, including psychomotor function
(such as tracking, movement speed), cognitive function (attention, executive
function and planning) and object movement prediction. In addition, mood
changes and physiological measures were assessed, and MDMA levels were measured in blood,
sweat, urine and saliva. Studies already published were conducted according
to a placebo-controlled, cross-over, double-blind design and treatments
included placebo, 75 mg MDMA and 0.5 g/kg alcohol.
Last updated April 7, 2004.
- Brookhuis KA, De Waard D, Samyn N. (2004) Effects of MDMA (ecstasy), and multiple drugs use on (simulated) driving performance and traffic safety. Psychopharmacology (Berl). 2004 Jan 9 [Epub ahead of print]
- Lamers CT, Ramaekers JG, Muntjewerff ND, Sikkema KL, Samyn N, Read NL, Brookhuis KA, Riedel WJ. (2003) Dissociable effects of a single dose of ecstasy (MDMA) on psychomotor skills and attentional performance. J Psychopharmacol. 17(4):379-387.
- Samyn N, De Boeck G, Wood M, Lamers C, De Waard D, Brookhuis K, Verstraete A, Riedel W (2002) Plasma, oral fluid and sweat wipe ecstasy concentrations in controlled and real life conditions. Forensic Sci Int 128: 90-97.
Effects of MDMA ("Ecstasy") on the Human Brain
Investigators: Franz Vollenweider, MD, Alex Gamma, PhD
Psychiatric University Hospital - Zürich, Switzerland
Contact:
Sponsors: Swiss National Science Foundation, UBS Science
Foundation
Psychobiologic studies including: assessment of possible
neurophysiological, psychological and cognitive alterations in chronic
MDMA users; evaluation of the role of serotonin, dopamine and
norepinephrine systems in mediating the effect of MDMA on mood,
psychomotor behavior and sensorimotor gating in humans, investigating
whether regular MDMA users show alterations in 5-HT reuptake site
densities indicative of neurotoxic effects after long-term MDMA use.
MAPS donated $6,000 to a sub-study in which 10 MDMA-naive subjects will
receive a PET scan to measure serotonin reuptake sites before and after
a single dose of MDMA (1.5-1.7mg/kg)
Last updated June 18, 2001
For details see the
MDMA Research in Switzerland Page
MDMA Pharmacokinetics in Humans
Investigators: John Mendelson, MD and Reese Jones, MD
UC San Francisco - California, USA
Contact person:
Sponsor: NIDA
Drug administration phase completed, eight subjects were given 0.5 and
1.5 mg/kg MDMA HCl. A paper from it is in press at Annals of Internal
Medicine. Data was presented at two
conferences.
Last updated September 18, 2000
See also Research in
Germany.
See the MDMA Research Page for more
links.
Clinical pharmacology of the interaction between alcohol and MDMA
Investigators: Jordi Camí, MD, Magi Farré, MD, et al.
Institut Municipal d'Investigacio Medica - Barcelona, Spain
Contact:
Sponsor: funded in part by several government grants
Psychobiologic study looking at the interaction of MDMA (100 mg) and alcohol (.8
g/kg).
Analysis nearly completed, papers being written. See
the current update.
Last updated September 14, 2000
Mood state and brain electric activity in Ecstasy users
Investigators: Alex Gamma, PhD, Edi Frei, Dietrich Lehmann (1), Roberto D. Pascual-Marqui (1), Daniel Hell and Franz Vollenweider, MD
Research Unit and (1) The KEY Institute for Brain-Mind Research, University
Hospital of Psychiatry, Zürich
Sponsors/Funding: Swiss National Science Foundation; Swiss Federal Health
Office; Heffter; MAPS.
Contact:
References
Neuroreport (2000) 11 (1): 157-162.
Last updated February 9, 2000
Gender Differences in the Subjective Effects of MDMA
Investigators: Liechti ME, Gamma A, Vollenweider, FX
Sponsors/Funding: Swiss National Science Foundation; Swiss Federal Health
Office; Heffter Research Institute
References: Psychopharmacology DOI (2001) 10.1007/s002130000648
Last updated February 16, 2001
Effects of MDMA (Ecstasy) on Prepulse Inhibition and Habituation of
Startle in Humans After Pretreatment with Citalopram, Halperidol, or
Ketanserin
Investigators: Liechti ME, Geyer MA, Hell D, Vollenweider FX
Sonsors/Funding: Swiss National Science Foundation; Swiss Federal Health
Office; Heffter Research Institute
References: Neuropsychopharmacology (2001) 24:240-252
Last updated February 16, 2001
MDMA and Memory
Investigators: Karen Bolla, PhD et al.
Johns Hopkins University - Baltimore, Maryland
Sponsor: NIH
Neuropsychological memory testing of MDMA users and controls.
Last updated April 9, 1999
Also see Alex Gamma - MDMA and Memory
Acute effects of 3, 4 - methylenedioxymethamphetamine (MDMA; "Ecstasy") on
cerebral blood flow (CBF), brain electric activity (EEG), prepulse inhibition
(PPI),
psychological state and neuropsychological performance in healthy subjects
Investigators: Alex Gamma, PhD, Franz Vollenweider, MD
Psychiatric University Hospital - Zürich, Switzerland
Sponsor: UBS Science Foundation and others
Contact: or
Aim: an integrative characterization of MDMA in terms of its acute
neurophysiological, psychological and cognitive effects in healthy,
MDMA-naive human subjects. Subjects were given a single oral dose of
MDMA (1.7 mg/kg).
Also see the references and details page.
Last updated January 18, 2000
Pharmacological Effects of MDMA in Humans
Investigator: Jordi Camí, MD, Magi Farré, MD, et al.
Institut Municipal d'Investigacio Medica - Barcelona, Spain
Contact: or
Sponsor: funded in part by several government grants
Studies include: Quantification of MDMA and its metabolites in plasma and urine
by gas
chromatography with nitrogen-phosphorus detection; Human pharmacology of MDMA,
Psychomotor performance and subjective effects.
Also see a list of published papers.
Last updated January 24, 2000
Low-dose MDMA ("Ecstasy") induces vasopressin secretion
Investigator: John Henry, MD
University College London, England
Contact:
This was a neurotoxicity study. Henry is directing additional MDMA studies at
this time.
Last updated January 14, 2000
- Fallon JK, Kicman AT, Henry JA, Milligan PJ, Cowan DA, Hutt AJ.
Stereospecific analysis and enantiomeric disposition of 3, 4-methylenedioxymethamphetamine (Ecstasy)
in humans. Clin Chem 1999 Jul;45(7):1058-69.
- Henry JA, Fallon JK, Kicman AT, Hutt AJ, Cowan DA, Forsling M
Low-dose
MDMA ("ecstasy") induces vasopressin secretion. Lancet 1998 Jun 13;351(9118):1784.
Psychobiologic Effects of MDMA in Humans
Investigators: Charles S. Grob, MD, and Russell E. Poland, PhD
Harbor-UCLA Medical Center - Torrance, California, USA
Sponsor: MAPS, Harbor/UCLA
Contact: ,
FDA-approved Phase 1 dose-response safety study .25 to 2.25 mg/kg, dose
administration
phase completed, data for .25 to .75 mg/kg published. Data for 1.00 to 2.25
mg/kg being
analysed for publication.
Also see the details and references page, and view the video.
Last updated January 19, 2000
MDMA Pharmacokinetics
Investigator: Rudolf Brenneisen, PhD
University of Bern, Switzerland
Contact:
Sponsor:NIH
PET scan study, MDMA Neurotoxicity, MDMA Users vs. Control Group.
Last updated April 9, 1999
MAPS Commentary on this study
MDMA Neurotoxicity Study Page from Erowid Entheogen Vaults
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See also Research in
Germany
Differential Cognitive and Brain Activation Effects of the Isomers of MDE
Investigators: Dr. Spitzer, et al.
University of Ulm, Germany
Contact:
This study was a double-blind, placebo-controlled investigation of the
cognitive and brain activation effects of the isomers of MDE. The researchers
concluded "The so-called entactogenic effects of MDE are likely to be caused
by the (S)-enantiomer, whereas (R)-MDE appears to be responsible for
neurotoxic effect."
Last updated January 29, 2002
The Psychological, Neuroendocrine, Cardiovascular and Sleep-EEG Effects of MDE
Investigators: Euphrosyne Gouzoulis-Mayfrank, MD et al.
Aachen, Germany
Contact:
Sponsor: DFG (Deutsche Forschungsgemeinschaft = German Research Foundation)
Human research on neurobiological and subjective effects of MDE. References and details.
Last updated February 18, 2003
- Gouzoulis-Mayfrank E, Thelen B, Maier S, Heekeren K, Kovar KA, Sass H,
Spitzer M. (2002) Effects of the
hallucinogen psilocybin on covert orienting of visual attention in humans.
Neuropsychobiology, 45:205-212.
- Gouzoulis-Mayfrank E, Schreckenberger M, Sabri O, Arning C, Thelen B, Spitzer M, Kovar KA, Hermle L, Bull U, Sass H (1999) Neurometabolic effects of psilocybin, 3,4- methylenedioxyethylamphetamine (MDE) and d-methamphetamine in healthy volunteers. A double-blind, placebo-controlled PET study with [18F]FDG. Neuropsychopharmacology 20: 565-81.
- Gouzoulis-Mayfrank E, Thelen B, Habermeyer E, Kunert HJ, Kovar KA, Lindenblatt H, Hermle L, Spitzer M, Sass H (1999) Psychopathological, neuroendocrine and autonomic effects of 3,4-methylenedioxyethylamphetamine (MDE), psilocybin and d-methamphetamine in healthy volunteers. Results of an experimental double-blind placebo-controlled study. Psychopharmacology (Berl) 142: 41-50.
- Schreckenberger M, Gouzoulis-Mayfrank E, Sabri O, Arning C, Zimny M, Zeggel T, Wagenknecht G, Kaiser HJ, Sass H, Buell U (1999) "Ecstasy"-induced changes of cerebral glucose metabolism and their correlation to acute psychopathology. An 18-FDG PET study. Eur J Nucl Med 26: 1572-9.
- Spitzer M, Franke B, Walter H, Buechler J, Wunderlich AP, Schwab M, Kovar K, Hermle L, Gron G (2001) Enantio-selective cognitive and brain activation effects of N-ethyl-3,4-methylenedioxyamphetamine in humans. Neuropharmacology 41: 263-71.
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Pharmacological, imaging and immunological studies of Ayahuasca in Healthy Volunteers
Investigators: Manel Barbanoj, MD, PhD and Jordi Riba
Institute de Recerca, Hospital de Sant Pau - Barcelona, Spain
Sponsor: Institut de Reserca, Hospital de la Santa Creu i Sant Pau (HSCSP)
Contact:
A study of the urinary excretion of ayahuasca alkaloids in the 22-volunteer, double-blind study (described below) is planned
but has not yet been conducted due to lack of funding. The double-blind brain-imaging study using SPECT to study regional
cerebral blood flow after ayahuasca administration has been fully approved and is now in progress. As of this
date, seventeen volunteers have undergone all experimental sessions. This study will also look for any immunomodulating effects of ayahuasca. These studies are
seeking additional information on mechanisms of action
underlying the central effects of ayahuasca.
Read the update in the MAPS Bulletin, Summer 2000 issue.
Last updated February 23, 2004
Ayahuasca in the Treatment of Substance Abuse
Investigators: Jacques Mabit, Jaime Torres, Rosa Giove, Javier Zavala, Olga
Celis
Takiwasi Center - Tarapoto, Peru
Contact:
Website:
www.takiwasi.com
Sponsors: Self-financed, funding sought from the French government, European
Union, and United Nations
Takiwasi has been doing research with substance abuse treatment for several
years.
Last updated March 5, 2003
-
"Blending Traditions - Using Indigenous Medicinal Knowledge to Treat Drug Addiction" - Jacques Mabit, M.D., MAPS Bulletin, Vol. 12 No. 2, Summer 2002. [PDF version]
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"Ayahuasca and Shamanism in Addiction Therapy" - Michel Mabit, MAPS Bulletin, Vol. 6 No. 3, Summer 1996
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"The Takiwasi Patient's Journey" - Michel Mabit, MAPS Bulletin, Vol. 6 No. 3., Summer 1996
A Study of Uniao do Vegetal (UDV) Adolescents
Investigators: Charles Grob, MD, Ailonso Luiza, Claudia Miranda, Glacus de
Souza
Brito, MD and Marlene de Rios
Sao Paulo, Brazil
Contact:
Sponsor: Heffter
Testing and evaluation of adolescents who have used ayahuasca and matched
controls have been completed. Data review now in process.
Last updated March 5, 2003
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Pharmacological Study of Ayahuasca in Healthy Humans
Investigators: Manel Barbanoj, MD, PhD and Jordi Riba
Institute de Recerca, Hospital de Sant Pau - Barcelona, Spain
Sponsor: Institut de Reserca, Hospital de la Santa Creu i Sant Pau (HSCSP), partial funding from Spanish government.
Contact:
A repeated dose study and a neurochemical mechanism study designed to evaluate the capacity of 5HT1A agonists and 5HT2A
antagonists to block the effects of ayahuasca will both be conducted soon. These studies are also included as part of
the program of research including a SPECT study of regional blood flow after ayahuasca that is already in progress, as described above.
Last updated February 20 2004
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EEG of Long-Term Ayahuasca Drinkers vs. Matched Controls
Investigators: Dr. Micheal Hessellink (Holland), Yatra da Silveira Barbosa
(Brazil), Dr. Erik Hofmann (Denmark). Co-investigators are: Dr. Glacos
Brito and Dr. Dartiu Xavier da Silveira both from Brazil.
Sao Paulo, Brazil
Contact:
The protocol has been completed and an article reporting on the results is published in the MAPS Bulletin, Spring 2001.
Last updated March 5, 2003
Pharmacological Study of Ayahuasca in Healthy Volunteers
Investigators: Manel Barbanoj, MD, PhD and Jordi Riba
Institute de Recerca, Hospital de Sant Pau - Barcelona, Spain
Sponsor: Institut de Reserca, Hospital de la Santa Creu i Sant Pau (HSCSP)
Contact:
The initial pilot study has been completed, including a published report of subjective effects in 6 volunteers.
An 18-subject, double-blind, placebo-controlled study of ayahuasca effects is now complete. Included were measures
of subjective effects, cardiovascular effects, sensorimotor gating, EEG variables, urinary monoamine metabolite
excretion, and pharmacokinetics of ayahuasca alkaloids.
Last updated May 9, 2003
- Riba J, Valle M, Urban G, Yritia M, Morte A, Barbanoj MJ (2003) Human Pharmacology of Ayahuasca: Subjective and cardiovascular effects, monoamine metabolite exretion, and Pharmacokinetics. JPET 306 (In Press)
- Riba, J et al. (2001) Subjective Effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers. Psychopharmacology 154:85-95.
- Riba J, Rodriguez-Fornells A, Barbanoj M (2002) Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively. Psychopharmacology (Berl), 165: 18-28
- Riba J, Anderer P, Morte A, Urbano G, Jane F, Saletu B, Barbanoj M (2002) Topographic pharmaco-EEG mapping of the effects of the South American psychoactive beverage ayahuasca in healthy volunteers. Brit J Clin Pharmacol 53: 613-628
- Yritia M, Riba J, Ortuno J, Ramirez A, Castillo A, Alfaro Y, de la Torre R, & Barbanoj MJ(2002): Determination of N,N-dimethyltryptamine and beta-carboline alkaloids in human plasma following oral administration of Ayahuasca Journal of Chromatography B 779:271-281
- "A Pharmacological
Study of Ayahuasca in Healthy Volunteers" - MAPS Bulletin, Vol. 8 No. 3, Autumn 1998
Investigations on the Human Psychopharmacology of Ayahuasca: Phase I
Investigators: Dennis J. McKenna, PhD and Charles S. Grob, MD
and Jace Callaway, PhD
Contact: and
Sponsor: Botanical Dimensions, Heffter, MAPS
Psychobiologic study, completed and published, follow-up studies possible.
Last updated March 5, 2003
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Human Psychopharmacology of N,N-dimethyltryptamine
Investigator: Rick Strassman, MD
University of New Mexico, USA
Contact:
Sponsor: NIDA
Psychobiological study, finished and published.
Last updated April 9, 1999
MAPS Bulletin - Volume 6 Number 1 Autumn 1995
University of New
Mexico Update
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Ibogaine treatment study with addiction
Investigator: Deborah Mash, PhD
St. Kitt, Virgin Islands
Contact:
Sponsor: Healing Visions Institute for Addiction Recovery, Ltd.
Sponsor: Healing Visions Institute for Addiction Recovery, Ltd.
Clinical study of the safety and efficacy of ibogaine in the treatment of addiction, with data gathered from patients treated by Dr. Mash, an expert in the study of ibogaine in human patient volunteers. To date, she has evaluated the effect of ibogaine in over three hundred patients. Due to a lack of funds, most of these data come from treatment conducted off-shore.
Last updated June 18, 2001
- Mash, D.C., Kovera, C.A. Pablo, J., Tyndale, R. F., Ervin, F.D., Williams,
I.C., Singleton, E.G., and Mayor, M.
Ibogaine: Complex Pharmacokinetics, Concerns for Safety, and Preliminary
Efficacy. Neurobiological Mechansisms of Drugs of Abuse, Annals New York Acad. Sci. Vol. 94: 394-401, 2000.
- Mash DC, Kovera CA, Buck BE, Norenberg MD, Shapshak P, Hearn WL, Sanchez-Ramos
J, (1998)
Medication Development of Ibogaine as a Pharmacotherapy for Drug
Dependence, Annals NY Acad Sci, v 844 pp 274-292.
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Outcome Study of Ibogaine in the Treatment of Addiction
Investigators: Valerie Mojeiko, Sandra Karpetas, Leah Martin, Jill Stammer, Randy Hencken
Sponsor: MAPS
Contact:
This study is in the protocol design stage and will use a similar methodology
to evaluate the outcomes of patients treated at both the Iboga
Therapy House in Vancouver and the clinic in Mexico run by the Ibogaine Association. For more information about ibogaine treatment, see "Case Studies of Ibogaine Treatment: Implications for Patient Management Strategies" by Lotsof and Alexander, from The Alkaloids series, vol. 56, IBOGAINE: PROCEEDINGS OF THE FIRST
INTERNATIONAL CONFERENCE, edited by Alper, Glick and Cordel.
Last Updated May 27, 2004
Safety studies in preparation for proposed study of ibogaine therapy
in the treatment of cocaine addiction
Investigators: Carlos Singer, MD and Deborah Mash, PhD
Unversity of Miami Medical School - Florida, USA
Contact
Continuation of a Phase 1 dose-response study to assess the safety, pharmacokinetics and dosage effects of ibogaine. The study will include a follow-up and standardized data collection in order to identify relevant parameters of efficacy. The study has stopped at 2 mg/kg, but has been approved for 4, 6 and 8 mg/kg. Research cannot begin until funding of about $500,000 is secured. Currently, there is no funding to continue this study.
view video
Last updated April 30, 2003
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There is additional information about ibogaine research at
www.ibogaine.org
Safety studies in preparation for proposed study of ibogaine therapy
in the treatment of cocaine addiction
Investigators: Juan Sanchez-Ramos, MD, PhD and Deborah Mash, PhD
Unversity of Miami Medical School - Florida, USA
Contact:
Sponsor: University of Miami, MAPS
Clinical study Phase I begun (up to 2 mg/kg), funding ceased,
published. view video
Last updated April 30, 2003
MAPS Bulletin - Volume 6 Number 3 Summer 1996
Phase 1 Clinical
Trial
of Ibogaine in Human Patient Volunteers
MAPS Bulletin - Volume 6 Number 1, Autumn 1995
Development of Ibogaine as an Anti-Addictive Drug:
A progress report from the University of Miami School of Medicine
MAPS Bulletin - Volume 5 Number 3 Winter 1994-95
Ibogaine in the treatment of chemical
dependence disorders: clinical perspectives
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Ketamine Psychedelic Therapy In The Treatment of Heroin Addiction
In this study, forty patients will be given 3 therapy sessions with
ketamine, while another forty patients will be given 3 therapy sessions, one with
ketamine and two without ketamine. MAPS and Heffter Research Institute have
jointly agreed to donate $9,450 each for five years to this study. MAPS and
Heffter have already donated for each of the first four years. Fifty-nine
patients have already been treated, and follow-up assessments have been performed on
patients already enrolled in this study so far. Unfortunately ketamine has
recently been rescheduled in Russia and this study has been shut down. Dr.
Krupitsky is trying to reopen the study but isn't sure yet whether this can be
accomplished.
Research Protocol for Single vs. Multiple Dose Study
Last updated October 31 2003
Ketamine Research in Russia Page (MAPS)
Krupitsky E, Burakov, A, Romanova, T, Dunaevsky, I, Strassman, R, Grinenko A (2002). Ketamine psychotherapy for heroin addiction: immediate effects and two-year follow-up. Journal of Substance Abuse Treatment 23, 273-283
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Ketamine Psychedelic Therapy in the Treatment of Heroin Addiction
Investigator: Evgeny Krupitsky, MD, PhD
St. Petersburg, Russia
Contact
Sponsor: MAPS, Heffter
Clinical study, drug administration phase completed, 70 patients treated
(35 in the experimental and 35 in the control group). The study is
finished, the researchers published the six-month follow-up paper
in MAPS. The one-year follow-up analysis has been completed. Two year
follow-up data has been analyzed and submitted for publication and is
currently in the midst of the peer review process. Results are promising.
Research Protocol for the Therapeutic dose vs. Low Dose Placebo study
Last updated May 6, 2003
Experiments in Altered Perception of 3-D Visual Illusions as a Screening
Method for
Psychedelic Activity Using Ketamine
Investigators: Torsten Passie, MD; Udo Schneider MD and Hinderk Emrich, MD
Hannover, Germany
Contact:
www.schamanismus-information.de
Sponsor: MAPS, Dept. of Psychiatry Hannover Medical School
Clinical experiment with ketamine to establish a paradigm to use visual 3-D
illusions as
screening instruments for detecting psychedelic activity in humans below the
subjective
threshold of experience. Passie's team has recently published a report relating to this research.
Last updated August 11, 2003
Passie T, Karst M, Borsutzky M, Wiese B,
Emrich HM, Schneider U (2003)Effects of different subanaesthetic doses of (S)-ketamine on psychopathology and binocular depth inversion in man. J Psychopharmacology 17: (2003) 51-56
Full Text in PDF Format
Antidepressant effects of ketamine in depressed patients
Investigators: Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney
DS,
Krystal JH
Abraham Ribicoff Center Clinical Neuroscience Research Unit of
theConnecticut Mental Health Center, New Haven 06519, USA Seven
subjects with major depression completed 2 test days that involved
intravenous treatment with ketamine hydrochloride (.5 mg/kg) or saline
solutions under randomized, double-blind conditions. RESULTS: Subjects
with depression evidenced significant improvement indepressive symptoms
within 72 hours after ketamine but not placebo infusion. CONCLUSIONS:
These results suggest a potential role for NMDA receptor-modulating
drugs in the treatment of depression.
Reference: Biol Psychiatry 2000 Feb 15;47(4):351-4.
Last updated April 12, 2000
Psychedelic effects of ketamine in healthy volunteers: relationship to
steady-state
plasma concentrations
Investigators: Bowdle TA, Radant AD, Cowley DS, Kharasch ED, Strassman RJ, Roy-
Byrne
PP
Department of Psychiatry, Harborview Medical Center, University of Washington,
Seattle
Contact:
Ketamine or saline was administered in a single-blinded crossover protocol to 10
psychiatrically healthy volunteers. Hallucinogen rating scale scores were
similar to those
found in a previous study with psychedelic doses of DMT.
Synopsis of paper in Anesthesiology (1998)
Last updated November 3, 1999
Ketamine Psychedelic Therapy in the Treatment of Alcoholics
Investigator: Evgeny Krupitsky, MD, PhD
St. Petersburg, Russia
Contact:
Sponsor: Leningrad Regional Center for Alcoholism and Drug Addiction Therapy,
MAPS
Ten years of clinical studies completed and published.
Last updated April 9, 1999
Ketamine Research in Russia Page (MAPS)
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Receptor Profiles of Lysergamides related to LSD
Investigator: David E. Nichols, PhD
Purdue University - West Lafayette, IN
Contact:
Sponsor: Heffter, Promind
Laboratory research, no human or animal subjects. It is well known that the nature of
the amide function of lysergamides is critical to conferring activity and high potency onto these
molecules. The N,N-diethylamide (LSD) is unique among all the known amides, both for the qualitative
aspects of its effects and for its extremely high potency.This project is evaluating a series of lysergamides
of varying amide structure using radioligand competition studies at cloned human brain neurotransmitter receptors
expressed in cell lines. The project seeks to identify in these data the possible reasons
for the high degree of variability in activity of the various amides. That is, is there a specific subset of receptors to which LSD binds
that less potent lysergamides do not? In addition, intracellular signaling pathways are being examined to determine whether all lysergamides
activate the same intracellular biochemical events.
Last updated April 9, 2003
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Psilocybin and LSD in the treatment and prevention of cluster headaches
Investigators: Dr. John Halpern and Dr. Andrew Sewell
Location: Harvard Medical School, McLean Hospital, Belmont, MA.
Sponsor: MAPS
Contact:
MAPS was approached in early 2004 by Bob Wold, a cluster headache patient advocate (http://www.clusterbusters.com), who has collected more than 50 case reports of people reporting very positive results in breaking cluster headache cycles and delaying the reoccurrance of cluster headaches through using psilocybin or LSD. At present, there are some medications that are used to stop cluster headaches, which are more severe than migraines. but they are not fully effective in many patients, and they do not prevent the cycling course of cluster headaches.
MAPS has recently received a donation of $50,000 to support research into this treatment approach from Marsha and Dave Weil, who hope that their donation will generate matching funds from other donors; potential donors can contact
for more information. The effort to design and obtain approval for a study will be led by Dr. John Halpern and Dr. Andrew Sewell, both at Harvard Medical School. Over the summer of 2004, they will write up a case series for publication in a medical journal. Starting in October 2004, they will begin the protocol design and approval process.
Last updated May 18, 2004.
LSD-Assisted Psychotherapy in the Treatment of Cancer Patients
Investigators: Albert A. Kurland, MD, Richard Yensen, PhD, and Donna A. Dryer,
MD
Orenda Institute, Baltimore, Maryland
Contact:
Sponsor: Orenda Institute, MAPS
Psychotherapy study designed to study the use of LSD-assisted psychotherapy in the treatment of depression and anxiety in cancer patients. The protocol was submitted to FDA on July 20, 2001. On August 22, 2001, FDA placed the protocol on Clinical Hold, requesting quite a few changes in the protocol design along with additional background information about prior LSD psychotherapy research. In mid-October 2001, in order to gather requested data for submission to FDA, MAPS staffer Brandy Doyle assisted Richard Yensen and Donna Dryer in reviewing the files of cancer patients treated with LSD in the late 1960s and early 1970s. No date has yet been set for the resubmission of a revised protocol to FDA.
Last updated December 24, 2001.
"B.C.'s Acid Flashback" - R.C., Vancouver Sun
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Since the discovery of the psychoactive effects of LSD in 1943, over 1000 papers
have been
published on a huge range of effects of LSD in humans and animals.
See the Psychedelic Bibliography
for more on these studies. You may also view references from Torsten Passie's psychedelic/psycholytic therapy database, also accessible through the psychedelic bibliography. To view this collection, either search "entire collection," or use "Expert search" and type "passie" as the requested database.
Follow-up study of Bastiaans LSD therapy
Investigators: Nicole Maalste, Hans Ossebaard
Utrecht, Netherlands
Contact:
Sponsor: MAPS, Promind Foundation
Retrospective survey study with former clients who were treated with
drug therapy by Dr. Jan Bastiaans. Data collection and analysis for
pilot study completed. Funding sought for further research.
Final Report: Summer 1999,
Progress Report: Winter 1999, Winter 2001.
Last updated March 25, 2002
Follow-up study of Janiger LSD research
Investigators: Rick Doblin, Jerry Beck, PhD, Kate Obata, Maureen Alioto
Los Angeles Area, California
Contact
Sponsor: MAPS
Retrospective survey study with 45 people who participated in the LSD
research of Dr. Oscar Janiger between 1954 and 1962.
The Janiger
LSD Follow-up Study was published by MAPS.
Last updated May 9, 1999
A Critical Review of Theories and Research Concerning
Lysergic Acid Diethylamide (LSD) and Mental Health
Investigator: David Abrahart
Contact:
A critical research literature review concerning LSD and mental health. In
particular it concentrates on flashbacks, precipitated psychoses and therapeutic uses.
Read it
Last updated August 25, 1999
Psycholytic Therapy with MDMA and LSD in Switzerland
Zürich, Switzerland
Investigators: Marianne Bloch, MD, Jurai Styk, MD and Dr. Samuel Widmer, MD
Sponsor: Swiss Medical Society for Psycholytic Therapy
From 1988 to 1993 therapists with the Swiss Medical Society for Psycholytic
Therapy
worked with MDMA and LSD as adjuncts to psychotherapy. The findings from this
study
were published in the MAPS Bulletin,
Winter 1994-
95.
Drs. Juraj and Sonja Styk discussed this work at the 1999 MAPS MDMA symposium in
Israel. Read their talk,
view video
Last updated January 14, 2000
A Critical Review of Theories and Research Concerning LSD and Mental Health
David Abrahart
Psychedelic-Assisted Psychotherapy for the Terminally Ill
Bruce Sewick
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Mescaline in Healthy Volunteers
Investigator: Dr. Roy Mathew
Duke University Medical School, Durham NC, USA
Sponsor: NIDA
Mescaline and PET scans in healthy normal psychedelic-experienced subjects.
Last updated February 7, 2002
"Tracing the Synapses of Our Spirituality", S. Vedantam, 17 July 2001, Washington Post. Features an interview with Dr. Mathew.
"Time" -- by Dr. Roy Mathew. MAPS - Volume 11, Number 2. Fall 2001.
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Blood flow and cerebral laterality in the mescaline model of
psychosis
Investigators: Hermle L, Gouzoulis-Mayfrank E, Spitzer M
Department of Psychiatry, Christophsbad, Goppingen, Germany.
Abstract of published
paper
Last updated February 22, 2000
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Peyote Neuropsychological Study
Investigator: John Halpern, MD, Harrison Pope, MD
Harvard Medical School - Cambridge, Massachussetts
Contact:
Sponsor: Heffter, NIDA, Harvard Medical School, MAPS
Investigators have begun neuropsychological testing with Native American Church
members. Pilot data has been analysed. MAPS donated $10,000 towards this study in May, 2001.
Last updated Febrary 7, 2002
MAPS Bulletin -- Volume 11, Number 2 Fall 2001.
"Research at Harvard Medical School" -- by Dr. John Halpern
"Interview with John Halpern" -- by Valerie M.
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Psilocybin in the treatment of cancer patients
Investigator: Charles Grob, MD, UCLA-Harbor Medical Center - Torrance, CA
Contact:
Web: www.canceranxietystudy.org
Sponsor: Heffter
Grob has prepared a study investigating whether anxiety in the dying can be significantly reduced by
the appropriate administration of psilocybin. Any attendant reduction
in pain will also be measured. The study is now fully approved, and Grob is seeking people interested in participating in this study. People interested in participating may learn more about volunteering here or at the study website.
Last updated March 25, 2004
Psilocybin in the Treatment of Obsessive-Compulsive Disorder
Investigator: Francisco Moreno, MD
University of Arizona, Tucson, USA
Contact:
Sponsor: Heffter/MAPS
This is the first FDA-approved study in more than 25 years to examine the use of psilocybin in a patient population. The principal investigators plan to study the use of psilocybin in 10 patients suffering from obsessive-compulsive disorder (OCD). They want to determine if they can replicate in a clinical study several published case reports of patients whose OCD symptoms were reduced after self- experimentation with psilocybin mushrooms. MAPS has paid $12,250 for the synthesis of one gram of psilocybin. Analytical data on this psilocybin has been submitted to FDA in March, 2001, with approval obtained from the FDA on May 9, 2001. DEA licenses received July 2, 2001. First patient was treated on November 27, 2001; eight subjects have been treated thus far, in a total of 29 sessions. Current news
on this study, Study Protocol,
Informed Consent Form
Last updated February 10, 2004
Experimental Studies in the Effects of Psilocybin on Binocular
Depth Inversion, Binocular Rivalry, Neuropsychology and Synaesthesias
Investigators: Torsten Passie M.D.; Jürgen Seifert M.D., Udo
Schneider M.D., Hinderk M. Emrich M.D., Ph.D.
Medical School Hannover, Dept. of Clinical Psychiatry and Psychotherapy,
Hannover, Germany
Contact:
Web: www.schamanismus-information.de
Sponsor: MAPS/Medical School Hannover, Dept. of Clinical Psychiatry and
Psychotherapy
This is a study in 12 healthy physicians with medium doses of psilocybin examining effects of psilocybin on different neuropsychological measures, and perceptual changes and some subjective effects. These measures include binocular rivalry (different information presented to each eye) and the "hollow mask" paradigm. The study is double-blind and placebo-controlled (active placebo). The process of permission is completed and the study is fully approved. MAPS has donated $3,000 for the purchase of 250 milligrams of psilocybin, insurance, and other expenses. Three of twelve subjects have now been enrolled in this study.
Read more about this study
Last updated August 20, 2003
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Psilocybin and LSD in the treatment and prevention of cluster headaches
Investigators: Dr. John Halpern and Dr. Andrew Sewell
Location: Harvard Medical School, McLean Hospital, Belmont, MA.
Sponsor: MAPS
Contact:
MAPS was approached in early 2004 by Bob Wold, a cluster headache patient advocate (http://www.clusterbusters.com), who has collected more than 50 case reports of people reporting very positive results in breaking cluster headache cycles and delaying the reoccurrance of cluster headaches through using psilocybin or LSD. At present, there are some medications that are used to stop cluster headaches, which are more severe than migraines. but they are not fully effective in many patients, and they do not prevent the cycling course of cluster headaches.
MAPS has recently received a donation of $50,000 to support research into this treatment approach from Marsha and Dave Weil, who hope that their donation will generate matching funds from other donors potential donors can contact for more information. The effort to design and obtain approval for a study will be led by Dr. John Halpern and Dr. Andrew Sewell, both at Harvard Medical School. Over the summer of 2004, they will write up a case series for publication in a medical journal. Starting in October 2004, they will begin the protocol design and approval process.
Last updated May 18, 2004.
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Psilocybin: Basic Dose-Response Safety Studies
Investigator: Franz Vollenweider, MD
Psychiatric University Hospital Zurich, Switzerland
Contact:
Sponsor: Heffter
Dr. Vollenweider's team have completed a series of basic research studies into the dose-response effects of psilocybin on physiological and psychological measures, cognition, sensorimotor gating, sequential behaviour, and brain activity in healthy human subjects. Fifty-six individuals were examined after a range of doses of psilocybin. A paper reporting the effects of placebo, very low, low, medium and high doses of psilocybin (45 -315 mcg/kg) in eight individuals has been published on-line in November 2003 and in print in March 2004. The researchers assessed subjective, physiological and neuroendocrine effects of psilocybin, including an assessment of attention.
Last updated March 18, 2004
- Hasler F , Grimberg U, Benz MA, Huber T, Vollenweider FX (2004) Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose-effect study. Psychopharmacology (Berl) 172: 145-156. Published on-line DOI: 10.1007/s00213-003-1640-6
View the full text in PDF format.
The Concord Prison Experiment Experiment Follow-Up
Investigator: Rick Doblin, Ph.D.
This study, originally published in the Journal of Psychoactive Drugs [Oct-Dec
1998] is one in a series of long-term follow-ups to early psychedelic research that
MAPS has sponsored. The original 1961-63 Harvard study lead by Dr. Timothy Leary
investigated the utility of psilocybin in reducing rates of recidivism for
prisoners.
Article from MAPS Bulletin
Leary Riedlinger Report
Last updated Jan 3, 2000
The Good Friday Experiment Follow-Up
Investigator: Rick Doblin, Ph.D.
Contact:
This study, originally published in the Journal of Transpersonal Psychology
[1991 Vol
23(1)] is one in a series of long-term follow-ups to early psychedelic research
that MAPS
has sponsored. The original 1962 Harvard study lead by Walter Pahnke
investigated the
utility of psilocybin in triggering a mystical experience.
Article in the Schaffer
Library
of Drug Policy
Last updated Jan 3, 2000
Psilocybin's effects on cognition
Investigator: Manfred Spitzer, MD, PhD et al.
Psychiatrische Universitats Klinic, Heidelberg, Germany
Human clinical study, completed and published.
More psilocybin
research
in Germany
Last updated April 9, 1999
- Spitzer M, et al. (1996)
Increased activation of indirect semantic associations under psilocybin. Biol Psychiatry. 1996 Jun 15;39(12):1055-7.
Psilocybin's
effects on cognition: Recent research and its implications for enhancing creativity -- MAPS Bulletin, Volume 7, Number 1 Winter 1996/97
Human Psychopharmacology of Psilocybin
Investigator: Rick Strassman, MD
University of New Mexico, USA
Psychobiological study. Phase 1 dose-response study
Sponsor: NIDA
Begun, not completed due to personal reasons unrelated to study itself.
Last updated April 9, 1999
University of New
Mexico Update -- MAPS Bulletin, Volume 6, Number 1 Autumn 1995
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Meditation with Salvia Divinorum/Salvinorin A
Investigators: Ian Soutar, Rick Strassman, M.D.
Contact:
Sponsor: MAPS
This project evaluates Salvia divinorum as a tool for enhancing
meditation work. Buddhist, Quaker, Sufi and other meditation techniques
are used by participants in this double blind evaluation of group
meditation combined with low doses of Salvia divinorum. One third of the
subjects will receive a placebo, one third will receive a very low dose
and one third will receive a low dose.
MAPS has purchased the materials and paid for the chemical analysis.
Continuing assistance is being offered at no charge, in the spirit of
amateur research, by MAPS (professional) members. Thanks to all who are
currently contributing their knowledge to this project. Details on this study.
Last updated June 18, 2001
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Differential Effects of Hallucinogens, Entactogens, and Psychostimulants
Investigators: Euphrosyne Gouzoulis-Mayfrank, MD and Mark Geyer, PhD
Aachen, Germany and UC San Diego - La Jolla, California
Contact:
Sponsor: Heffter
A study with healthy volunteers with two different hallucinogens and
placebo in a double- blind, cross-over design. The aim of thestudy is to
compare the effects of a classic tryptamine hallucinogen
onpsychosis-like psychopathology and measures of early information
processing tothe effects of an NMDA-antagonist.
References and details
Last updated February 22, 2000
Receptor Mechanisms Contributing to Psychedelic Drug Effects
Investigators: Franz Vollenweider, MD and Mark Geyer, PhD
Psychiatric University Hospital - Zürich, Switzerland and UC San Diego - La
Jolla,
California
Contact:
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Sponsor: Heffter
Last updated April 9, 1999
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A Biochemical Bridge to the Embodied Psyche:
LSD Research 1945-1965 (doctoral dissertation)
Investigator: Kim Hewitt
Department of American Civilization, University of Texas at Austin
Contact:
Sponsors: MAPS
Exploration of how psychedelics helped facilitate a shift in American
ideas about mind- body interaction. In 1999 the investigator traveled to
the American Medical Archives in Chicago, and the Rockefeller Institute
Archives in Tarrytown, New York to do research for this project, and
presented part of her research on LSD at St. Lawrence University in
Canton, New York for a series called "Visions the Plants Gave Us." Part
of my dissertation will be published in an anthology called "The
Politics of Healing," to be published in 2002. My essay addresses how
psychedelic therapy changed individuals and the cultural mindset during
the 1950's-60's. It is entitled "Solvents of Conceptual Sludge:
Psychedelic Therapy Confronting the Cold War Mindset."
Read about this
study in the MAPS Bulletin
Last updated May 24, 2001
Insight, Integration and Implementation: The Personal Psychospiritual
Uses of Entheogens by Mental Health Professionals (doctoral
dissertation)
Investigator: Sean House
University of Idaho, Counselor Education
Qualitative study of the processes by which entheogen use becomes
therapeutic. Explores how insights become implemented in daily living.
Development of a grounded theory outlining the therapeutic process.
Participants all have training in one of the mental health professions.
Last updated February 23, 2000
Sponsor: MAPS
Pilot interview study of adolecents and young adults who've grown up in a
psychedelic-
friendly households.
Read about this
study
in the MAPS Bulletin
Last updated April 9, 1999
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Northwest Amazonian Ayahuasca Shamanism and Near-Death Experience
Investigator: Marcus Lumby, PhD candidate
Contact:
Sponsorship: includes small grant from MAPS
Anthropological investigation, first phase completed. Read
Field Reports and
MAPS article.
Last updated June 8, 2000
The Role of Bwiti in West Africans' Psychospiritual, Social,
Ecological, Ancestral, and Cosmological Relationships (doctoral
dissertation)
Investigator: Larry Roussel
California Institute of Integral Studies, East-West Psychology
Sponsor: 1998 Kranzke Scholarship
Comparison of the religious use of iboga among the Bwiti with the ritual use of
plants in other syncretic religions such as the Native American Church
and the Santo Daime Church of Brazil which also use plant entheogens as
an integral part of their ceremonies.
Last updated April 9, 1999
Procedural Variables Needed to Achieve Therapeutic Gains
Through the Use of Psychedelics
Investigator: Brad Watkins
California Institute of Integral Studies, Integral Counseling Psychology
Program
Sponsor: 1998 Kranzke Scholarship
Analysis of published research studies in which psychedelics were used to treat
neurosis
and addiction, and will analyze the treatment procedures to discover the
relationship
between procedural variables and their outcomes.
Last updated April 9, 1999
The Use of Calea Zacatechichi in the Induction of Lucid
Dreams and Enhancement or Alteration of the Lucid Dream State
(doctoral dissertation)
California Institute of Integral Studies, Clinical Psychology
Investigator: David Stuckey
Sponsor: 1998 Kranzke Scholarship
Last updated April 9, 1999
Guided, Structured, Group Use of Entheogenic Substances in Western Culture (doctoral dissertation)
Investigator: Roger Marsden
California Institute of Integral Studies, Clinical Psychology
Contact:
Sponsors: 1998 Kranzke Scholarship; MAPS
What are the different frameworks being employed by entheogenic guides?
How are these frameworks different from those used in the research of
the 1960s? How do the variations in present day frameworks appear to
affect the outcome? Regardless of one's individual assumption of the
value of psychedelic work, it is happening in a variety of contexts
across the planet. The investigator has completed all interviews in 3
guided, structured entheogen/psychedelic groups. Data anaysis is
complete (10 central themes extracted for the basis of discussion, i.e.,
preparation, integration, relationship of participants to guide, role of
relationship of participants to each other, description of the actual
sessions, relationship of the work to drug abuse issues, etc.)
Read about this
study in the MAPS Bulletin
Last updated January 19, 2000
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Yes, Mom Took Acid: The Sociohistorical Influence of Prior Psychedelic Drug
Use
(doctoral dissertation)
Investigator: Mariavittoria Mangini, M.S. PhD
Laytonville, California
Contact:
Qualitative study, using focused interviews to obtain narrative data.
Data also considered: published contemporary and historic discourses
about psychedelic drug use, accounts of the interactions of psychedelic
drug users with their social environment; and representations of the
psychedelic experience in art, music, film and the electronic media.
Mangini was one of fifty scholars nationwide awarded the American
Dissertation Fellowship by the American Association of University Women for
the 1999-2000 academic year, a heartening acknowledgement of the relevance of this topic.
Last updated April 11, 2001
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