Investigator: Evgeny Krupitsky MD, PhD., St. Petersburg, Russia
Sponsors: MAPS, Heffter
In this study, forty patients will be given 3 therapy sessions with ketamine, while another forty patients will be given 3 therapy sessions, one with ketamine and two without ketamine. MAPS and Heffter Research Institute have jointly agreed to donate $9,450 each for five years to this study. MAPS and Heffter have already donated for each of the first four years. Fifty-nine patients have already been treated, and follow-up assessments have been performed on patients already enrolled in this study so far. Unfortunately ketamine has recently been rescheduled in Russia and this study has been shut down. Dr. Krupitsky is trying to reopen the study but isn’t sure yet whether this can be accomplished.
Research Protocol for Single vs. Multiple Dose Study
- Ketamine Research in Russia Page (MAPS)
- Krupitsky E, Burakov, A, Romanova, T, Dunaevsky, I, Strassman, R, Grinenko A (2002). Ketamine psychotherapy for heroin addiction: immediate effects and two-year follow-up. Journal of Substance Abuse Treatment 23, 273-283.
- Krupitsky, EM, Burakof AM, Dunaevsky IV, Romanova TN, Slavina TY, Grinenko AY (2007). Single Versus Repeated Sessions of Ketamine-Assisted Therapy for People with Heroin Dependence. J Psychoactive Drugs 39(1): 13-19.
- Evegeny M. Krupitsky, M.D., Ph.D., Andrey M. Burakov, M.D., Ph.D., Tatyana N. Romanova, Ph.D., Nina I. Grinenko, M.D., Alexander Y. Grinenko, M.D., Ph.D., Jason Fletcher, M.A., Ismene L. Petrakis, M.D., and John H. Krystal, M.D. (2001). Attenuation of Ketamine Effects by Nimodipine Pretreatment in Recovering Ethanol Dependent Men: Psychopharmacologic Implications of the Interaction of NMDA and L-Type Calcium Channel Antagonists. Neuropsychopharmacology 25(6): 936-947