On February 21, 2014, the 15th subject was treated in our ongoing study in 24 U.S. veterans, fire fighters, and police officers with chronic, treatment-resistant PTSD. The 16th subject was enrolled on February 17, and received their first MDMA-assisted psychotherapy treatment on February 24. Both of these subjects have also enrolled in our new physiological effects sub-study, which will measure the physiological effects of MDMA-assisted psychotherapy using heart rate variability (HRV) and functional magnetic resonance imaging (fMRI) and explore correlations with clinical outcomes.